Dual CEA/CD44 targeting to colorectal cancer cells using nanobody-conjugated hyaluronic acid-modified mesoporous silica nanoparticles with pH- and redox-sensitivity
نویسندگان
چکیده
Mesoporous silica nanoparticles (MSNs) loaded with doxorubicin and then modified hyaluronic acid (HA) nanobody (DOX@MSNs-HA-11C12) is a pH- redox-responsive drug delivery system, resulting in over 90% of LoVo cell apoptosis within 48 h.
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ژورنال
عنوان ژورنال: Materials advances
سال: 2022
ISSN: ['2633-5409']
DOI: https://doi.org/10.1039/d2ma00082b